hello replied: "Yes, and I have Antiphospholipid Antibody Syndrome (APS). The same disease that you have.
You may be Coumadin resistent. But also there is a lot of information that the finger prick machines are not accruate for APS patients. They all carry disclaimers on them. So you may want your doctor to do a vein draw to compare them. Are you seeing a hematologist? They may want to do a Factor X essay and compare that to your INR/PT
Typically most patients are kept at an INR of 3-4 with this disease. My INRs are hard to regulate. That is just part of APS. And since you are a woman, our hormones also play a role. Actaully, in the post partum period with the disease you are at some of the highest risk of clotting of than the pregnancy itself.
Here is a wonderful beginners guide to APS:. Here is some basic information on APS:
My INR is kept at 3.5-4.5 plus I take aspirin because APS can cause both venous and arterial clotting. I am also on Plaquenil. Do you keep a INR log book and medical symptoms journal? It is amazing the patterns we can find.
There is a non-profit organization in the US that can help you. There name is APS Foundation of America, Inc. Their link is below.
Good Luck!"
joe replied: "i too have started the coumadin "program" and have been on it for about 45 days. i started getting pricked every 2 to 3 days and am now up to every 2 weeks so hang in there you are not alone and sooner or later things will fall into place. my protime was 2.4 last week so it will work."
Does the change in seasons affect your INR levels? I've been taking Coumadin for my genetic blood disorder for some time now, and lately, there was no change in my diet since my last blood-screening, and I had been taking my doses regularly.
However, my last blood-screening had me reading a 2.8, and today's (March 14th), was an odd 4.1.
I told the tech on call everything I previously listed, but wonder if the change in seasons might have some affect on my levels.
Any ideas?
midget giraffe replied: "There is seasonal variation, with increased coagulation (and therefore a decreased INR) with colder temperatures. However, this is a fairly small effect and isn't likely to be the only cause of such a large change."
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